BDBM50417723 CHEMBL1644208

SMILES: COc1nc(NCCc2ccc(Cl)cc2Cl)cc(n1)-c1cc(ccc1F)C(C)(C)C(O)=O

InChI Key: InChIKey=AWZWXWUFDXJWRX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50417723   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostanoid DP receptor (Homo sapiens (Human))	BDBM50417723 (CHEMBL1644208) Show SMILES COc1nc(NCCc2ccc(Cl)cc2Cl)cc(n1)-c1cc(ccc1F)C(C)(C)C(O)=O Show InChI InChI=1S/C23H22Cl2FN3O3/c1-23(2,21(30)31)14-5-7-18(26)16(10-14)19-12-20(29-22(28-19)32-3)27-9-8-13-4-6-15(24)11-17(13)25/h4-7,10-12H,8-9H2,1-3H3,(H,30,31)(H,27,28,29)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.501	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Aventis US Curated by ChEMBL					Assay Description Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...				Bioorg Med Chem Lett 21: 66-75 (2010) Article DOI: 10.1016/j.bmcl.2010.11.071 BindingDB Entry DOI: 10.7270/Q22F7PPM
					More data for this Ligand-Target Pair