BDBM50417725 CHEMBL1644211

SMILES: COc1nc(NCCc2ccc(Cl)cc2Cl)cc(n1)-c1cccc(c1)C(C)(C)c1nnn[nH]1

InChI Key: InChIKey=ZFVUYHLQCIOXNZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50417725   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostanoid DP receptor (Homo sapiens (Human))	BDBM50417725 (CHEMBL1644211) Show SMILES COc1nc(NCCc2ccc(Cl)cc2Cl)cc(n1)-c1cccc(c1)C(C)(C)c1nnn[nH]1 Show InChI InChI=1S/C23H23Cl2N7O/c1-23(2,21-29-31-32-30-21)16-6-4-5-15(11-16)19-13-20(28-22(27-19)33-3)26-10-9-14-7-8-17(24)12-18(14)25/h4-8,11-13H,9-10H2,1-3H3,(H,26,27,28)(H,29,30,31,32)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.398	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Aventis US Curated by ChEMBL					Assay Description Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...				Bioorg Med Chem Lett 21: 66-75 (2010) Article DOI: 10.1016/j.bmcl.2010.11.071 BindingDB Entry DOI: 10.7270/Q22F7PPM
					More data for this Ligand-Target Pair