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SMILES: CCN[C@H]1CCC[C@@H](C1)Oc1ccc2c(cc[nH]c2=O)c1

InChI Key: InChIKey=FEJUGHZVLDTRTJ-KBPBESRZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50417850   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Rho-associated protein kinase 1


(Homo sapiens (Human))		BDBM50417850
PNG
(CHEMBL1667978)
Show SMILES CCN[C@H]1CCC[C@@H](C1)Oc1ccc2c(cc[nH]c2=O)c1 |r|
Show InChI InChI=1S/C17H22N2O2/c1-2-18-13-4-3-5-14(11-13)21-15-6-7-16-12(10-15)8-9-19-17(16)20/h6-10,13-14,18H,2-5,11H2,1H3,(H,19,20)/t13-,14-/m0/s1
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n/an/a 120n/an/an/an/an/an/a



MSD

Curated by ChEMBL


Assay Description
Inhibition of ROCK1 by IMAP assay

Bioorg Med Chem Lett 21: 1084-8 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.104
BindingDB Entry DOI: 10.7270/Q2DN468G
More data for this
Ligand-Target Pair