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SMILES: Cc1cc2c(cc[nH]c2=O)cc1O[C@H]1CCCNC1

InChI Key: InChIKey=PAPAQGYVXRMLPZ-LBPRGKRZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50417853   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Rho-associated protein kinase 1


(Homo sapiens (Human))		BDBM50417853
PNG
(CHEMBL1667975)
Show SMILES Cc1cc2c(cc[nH]c2=O)cc1O[C@H]1CCCNC1 |r|
Show InChI InChI=1S/C15H18N2O2/c1-10-7-13-11(4-6-17-15(13)18)8-14(10)19-12-3-2-5-16-9-12/h4,6-8,12,16H,2-3,5,9H2,1H3,(H,17,18)/t12-/m0/s1
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PC cid
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Similars
Article
PubMed
n/an/a 47.9n/an/an/an/an/an/a



MSD

Curated by ChEMBL


Assay Description
Inhibition of ROCK1 by IMAP assay

Bioorg Med Chem Lett 21: 1084-8 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.104
BindingDB Entry DOI: 10.7270/Q2DN468G
More data for this
Ligand-Target Pair