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SMILES: Cc1c[nH]c(=O)c2ccc(O[C@H]3CCCNC3)cc12

InChI Key: InChIKey=OEOGSEJIWYSSJE-LBPRGKRZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50417854   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Rho-associated protein kinase 1


(Homo sapiens (Human))		BDBM50417854
PNG
(CHEMBL1667974)
Show SMILES Cc1c[nH]c(=O)c2ccc(O[C@H]3CCCNC3)cc12 |r|
Show InChI InChI=1S/C15H18N2O2/c1-10-8-17-15(18)13-5-4-11(7-14(10)13)19-12-3-2-6-16-9-12/h4-5,7-8,12,16H,2-3,6,9H2,1H3,(H,17,18)/t12-/m0/s1
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PubMed
n/an/a 589n/an/an/an/an/an/a



MSD

Curated by ChEMBL


Assay Description
Inhibition of ROCK1 by IMAP assay

Bioorg Med Chem Lett 21: 1084-8 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.104
BindingDB Entry DOI: 10.7270/Q2DN468G
More data for this
Ligand-Target Pair