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SMILES: O=c1[nH]ccc2cc(O[C@H]3CCNC3)ccc12

InChI Key: InChIKey=MJHLFDZNTKULCZ-NSHDSACASA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50417856   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Rho-associated protein kinase 1


(Homo sapiens (Human))		BDBM50417856
PNG
(CHEMBL1667972)
Show SMILES O=c1[nH]ccc2cc(O[C@H]3CCNC3)ccc12 |r|
Show InChI InChI=1S/C13H14N2O2/c16-13-12-2-1-10(7-9(12)3-6-15-13)17-11-4-5-14-8-11/h1-3,6-7,11,14H,4-5,8H2,(H,15,16)/t11-/m0/s1
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Article
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n/an/a 525n/an/an/an/an/an/a



MSD

Curated by ChEMBL


Assay Description
Inhibition of ROCK1 by IMAP assay

Bioorg Med Chem Lett 21: 1084-8 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.104
BindingDB Entry DOI: 10.7270/Q2DN468G
More data for this
Ligand-Target Pair