BDBM50417904 CHEMBL1668568::US8618114, 1.1.6(1)

SMILES: CSc1nn2c(CO)cc(C)nc2c1S(=O)(=O)c1ccccc1

InChI Key: InChIKey=QKGIEOVAASUNSI-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50417904   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417904 (CHEMBL1668568 | US8618114, 1.1.6(1)) Show SMILES CSc1nn2c(CO)cc(C)nc2c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C15H15N3O3S2/c1-10-8-11(9-19)18-14(16-10)13(15(17-18)22-2)23(20,21)12-6-4-3-5-7-12/h3-8,19H,9H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.562	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP accumulation after ...				Bioorg Med Chem 19: 1482-91 (2011) Article DOI: 10.1016/j.bmc.2010.12.055 BindingDB Entry DOI: 10.7270/Q21G0NJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50417904 (CHEMBL1668568 | US8618114, 1.1.6(1)) Show SMILES CSc1nn2c(CO)cc(C)nc2c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C15H15N3O3S2/c1-10-8-11(9-19)18-14(16-10)13(15(17-18)22-2)23(20,21)12-6-4-3-5-7-12/h3-8,19H,9H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Determination of antagonistic activity of compounds of the general formula 1 towards 5-HT6 receptors. Compounds of the general formula 1 were tested ...				US Patent US8618114 (2013) BindingDB Entry DOI: 10.7270/Q2B56HD9
					More data for this Ligand-Target Pair