BDBM50418056 CHEMBL1688944

SMILES: CC(C)(C)c1cn(CCCc2cnc[nH]2)nn1

InChI Key: InChIKey=ZFDZUBGJLKYAKC-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50418056   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50418056 (CHEMBL1688944) Show SMILES CC(C)(C)c1cn(CCCc2cnc[nH]2)nn1 Show InChI InChI=1S/C12H19N5/c1-12(2,3)11-8-17(16-15-11)6-4-5-10-7-13-9-14-10/h7-9H,4-6H2,1-3H3,(H,13,14)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
VU University Amsterdam Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293 cells after 60 mins by liquid scintillation counting				J Med Chem 54: 1693-703 (2011) Article DOI: 10.1021/jm1013488 BindingDB Entry DOI: 10.7270/Q20G3MDD
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50418056 (CHEMBL1688944) Show SMILES CC(C)(C)c1cn(CCCc2cnc[nH]2)nn1 Show InChI InChI=1S/C12H19N5/c1-12(2,3)11-8-17(16-15-11)6-4-5-10-7-13-9-14-10/h7-9H,4-6H2,1-3H3,(H,13,14)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	191	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
VU University Amsterdam Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in HEK293 cells after 60 mins by liquid scintillation counting				J Med Chem 54: 1693-703 (2011) Article DOI: 10.1021/jm1013488 BindingDB Entry DOI: 10.7270/Q20G3MDD
					More data for this Ligand-Target Pair