BDBM50418076 CHEMBL1688985

SMILES: Clc1ccc(Cn2cc(CCCc3cnc[nH]3)nn2)cc1Cl

InChI Key: InChIKey=WLZIEQKPOAKLAQ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50418076   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50418076 (CHEMBL1688985) Show SMILES Clc1ccc(Cn2cc(CCCc3cnc[nH]3)nn2)cc1Cl Show InChI InChI=1S/C15H15Cl2N5/c16-14-5-4-11(6-15(14)17)8-22-9-13(20-21-22)3-1-2-12-7-18-10-19-12/h4-7,9-10H,1-3,8H2,(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	447	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
VU University Amsterdam Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293 cells after 60 mins by liquid scintillation counting				J Med Chem 54: 1693-703 (2011) Article DOI: 10.1021/jm1013488 BindingDB Entry DOI: 10.7270/Q20G3MDD
					More data for this Ligand-Target Pair