BDBM50418178 CHEMBL1761505

SMILES: NC(=O)c1cc(cc2cc[nH]c12)-c1cccc(CO)c1

InChI Key: InChIKey=OZUKSMOQTGVDDM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50418178   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inhibitor of nuclear factor kappa-B kinase subunit alpha (Homo sapiens (Human))	BDBM50418178 (CHEMBL1761505) Show SMILES NC(=O)c1cc(cc2cc[nH]c12)-c1cccc(CO)c1 Show InChI InChI=1S/C16H14N2O2/c17-16(20)14-8-13(7-12-4-5-18-15(12)14)11-3-1-2-10(6-11)9-19/h1-8,18-19H,9H2,(H2,17,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of IKK-alpha				Bioorg Med Chem Lett 21: 2255-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.107 BindingDB Entry DOI: 10.7270/Q2GF0VS3
					More data for this Ligand-Target Pair
Inhibitor of nuclear factor kappa-B kinase subunit beta (Homo sapiens (Human))	BDBM50418178 (CHEMBL1761505) Show SMILES NC(=O)c1cc(cc2cc[nH]c12)-c1cccc(CO)c1 Show InChI InChI=1S/C16H14N2O2/c17-16(20)14-8-13(7-12-4-5-18-15(12)14)11-3-1-2-10(6-11)9-19/h1-8,18-19H,9H2,(H2,17,20)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of IKK-beta				Bioorg Med Chem Lett 21: 2255-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.107 BindingDB Entry DOI: 10.7270/Q2GF0VS3
					More data for this Ligand-Target Pair