BDBM50418226 CHEMBL1760648

SMILES: CC(C)(CO)CNC(=O)c1cc2cc(ccc2n1Cc1cc(Cl)cc(Cl)c1)C#N

InChI Key: InChIKey=VMQPWINCJCWTLF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50418226   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50418226 (CHEMBL1760648) Show SMILES CC(C)(CO)CNC(=O)c1cc2cc(ccc2n1Cc1cc(Cl)cc(Cl)c1)C#N Show InChI InChI=1S/C22H21Cl2N3O2/c1-22(2,13-28)12-26-21(29)20-8-16-5-14(10-25)3-4-19(16)27(20)11-15-6-17(23)9-18(24)7-15/h3-9,28H,11-13H2,1-2H3,(H,26,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.37	n/a	n/a	n/a	n/a	n/a	n/a
MSD Curated by ChEMBL					Assay Description Antagonist activity against human CB1 receptor				Bioorg Med Chem Lett 21: 2034-9 (2011) Article DOI: 10.1016/j.bmcl.2011.02.019 BindingDB Entry DOI: 10.7270/Q27082PM
					More data for this Ligand-Target Pair