BDBM50418276 CHEMBL1767142

SMILES: CN1CCC[C@@H]1Cn1nc(Cc2ccc(cc2)C(C)(C)C)c2ccccc2c1=O

InChI Key: InChIKey=DXZJJDOMGLPHDI-HXUWFJFHSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50418276   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Homo sapiens (Human))	BDBM50418276 (CHEMBL1767142) Show SMILES CN1CCC[C@@H]1Cn1nc(Cc2ccc(cc2)C(C)(C)C)c2ccccc2c1=O |r| Show InChI InChI=1S/C25H31N3O/c1-25(2,3)19-13-11-18(12-14-19)16-23-21-9-5-6-10-22(21)24(29)28(26-23)17-20-8-7-15-27(20)4/h5-6,9-14,20H,7-8,15-17H2,1-4H3/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular cal...				J Med Chem 54: 2183-95 (2011) Article DOI: 10.1021/jm1013874 BindingDB Entry DOI: 10.7270/Q2GQ6Z2Z
					More data for this Ligand-Target Pair