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BDBM50418358 CHEMBL1770303

SMILES: Oc1ccccc1C(=O)NC(C(=O)Nc1ccccc1)c1ccc(Cl)cc1

InChI Key: InChIKey=AIVTXGMGZMXUBO-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50418358   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
fMet-Leu-Phe receptor 1/2


(Homo sapiens (Human))
BDBM50418358
PNG
(CHEMBL1770303)
Show SMILES Oc1ccccc1C(=O)NC(C(=O)Nc1ccccc1)c1ccc(Cl)cc1
Show InChI InChI=1S/C21H17ClN2O3/c22-15-12-10-14(11-13-15)19(21(27)23-16-6-2-1-3-7-16)24-20(26)17-8-4-5-9-18(17)25/h1-13,19,25H,(H,23,27)(H,24,26)
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KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.01E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Intrinsic activity at FPR1 in human neutrophils assessed as increase in calcium mobilization by FLIPR assay relative to fMLF


Bioorg Med Chem Lett 21: 2991-7 (2011)


Article DOI: 10.1016/j.bmcl.2011.03.049
BindingDB Entry DOI: 10.7270/Q2PZ5B2D
More data for this
Ligand-Target Pair