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BDBM50418359 CHEMBL1770302

SMILES: Cc1cccc(C)c1NC(=O)C(NC(=O)c1ccccc1O)C1CCCCC1

InChI Key: InChIKey=PABSTEZRMVQWFB-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50418359   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
fMet-Leu-Phe receptor 1/2


(Homo sapiens (Human))
BDBM50418359
PNG
(CHEMBL1770302)
Show SMILES Cc1cccc(C)c1NC(=O)C(NC(=O)c1ccccc1O)C1CCCCC1
Show InChI InChI=1S/C23H28N2O3/c1-15-9-8-10-16(2)20(15)24-23(28)21(17-11-4-3-5-12-17)25-22(27)18-13-6-7-14-19(18)26/h6-10,13-14,17,21,26H,3-5,11-12H2,1-2H3,(H,24,28)(H,25,27)
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KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 794n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Intrinsic activity at FPR1 in human neutrophils assessed as increase in calcium mobilization by FLIPR assay relative to fMLF


Bioorg Med Chem Lett 21: 2991-7 (2011)


Article DOI: 10.1016/j.bmcl.2011.03.049
BindingDB Entry DOI: 10.7270/Q2PZ5B2D
More data for this
Ligand-Target Pair