BDBM50418452 CHEMBL1783252

SMILES: CCCNC(=O)c1nnc2c(cccc2c1N)-c1cc(C)cc(C)c1

InChI Key: InChIKey=IACRYXFWKJOMEI-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50418452   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-2/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50418452 (CHEMBL1783252) Show SMILES CCCNC(=O)c1nnc2c(cccc2c1N)-c1cc(C)cc(C)c1 Show InChI InChI=1S/C20H22N4O/c1-4-8-22-20(25)19-17(21)16-7-5-6-15(18(16)23-24-19)14-10-12(2)9-13(3)11-14/h5-7,9-11H,4,8H2,1-3H3,(H2,21,23)(H,22,25)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]flunitrazepam from benzodiazepine binding site GABAA alpha2beta3gamma2 receptor expressed in Sf9 cells after 1 hr				Bioorg Med Chem 19: 2927-38 (2011) Article DOI: 10.1016/j.bmc.2011.03.035 BindingDB Entry DOI: 10.7270/Q29S1S98
					More data for this Ligand-Target Pair