BDBM50418463 CHEMBL1783263

SMILES: CCC(C)NC(=O)c1nnc2c(cccc2c1N)-c1cc(OC)ccc1OC

InChI Key: InChIKey=RMNTXVHSVPDCSC-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50418463   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-2/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50418463 (CHEMBL1783263) Show SMILES CCC(C)NC(=O)c1nnc2c(cccc2c1N)-c1cc(OC)ccc1OC Show InChI InChI=1S/C21H24N4O3/c1-5-12(2)23-21(26)20-18(22)15-8-6-7-14(19(15)24-25-20)16-11-13(27-3)9-10-17(16)28-4/h6-12H,5H2,1-4H3,(H2,22,24)(H,23,26)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	537	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]flunitrazepam from benzodiazepine binding site GABAA alpha2beta3gamma2 receptor expressed in Sf9 cells after 1 hr				Bioorg Med Chem 19: 2927-38 (2011) Article DOI: 10.1016/j.bmc.2011.03.035 BindingDB Entry DOI: 10.7270/Q29S1S98
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