BDBM50418468 CHEMBL1783268

SMILES: COc1ccc(OC)c(c1)-c1cccc2c(N)c3c(cn(C)c3=O)[nH]c12

InChI Key: InChIKey=AWNLWBAJAXHULP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50418468   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-2/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50418468 (CHEMBL1783268) Show SMILES COc1ccc(OC)c(c1)-c1cccc2c(N)c3c(cn(C)c3=O)[nH]c12 Show InChI InChI=1S/C20H19N3O3/c1-23-10-15-17(20(23)24)18(21)13-6-4-5-12(19(13)22-15)14-9-11(25-2)7-8-16(14)26-3/h4-10,22H,21H2,1-3H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	263	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]flunitrazepam from benzodiazepine binding site GABAA alpha2beta3gamma2 receptor expressed in Sf9 cells after 1 hr				Bioorg Med Chem 19: 2927-38 (2011) Article DOI: 10.1016/j.bmc.2011.03.035 BindingDB Entry DOI: 10.7270/Q29S1S98
					More data for this Ligand-Target Pair