BDBM50419068 CHEMBL1823879

SMILES: CCOc1ccccc1C(=O)NCC1(CCCCC1)N1CCN(CC1)C1CC1

InChI Key: InChIKey=NZCJBWNCSCYPKE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50419068   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Homo sapiens (Human))	BDBM50419068 (CHEMBL1823879) Show SMILES CCOc1ccccc1C(=O)NCC1(CCCCC1)N1CCN(CC1)C1CC1 Show InChI InChI=1S/C23H35N3O2/c1-2-28-21-9-5-4-8-20(21)22(27)24-18-23(12-6-3-7-13-23)26-16-14-25(15-17-26)19-10-11-19/h4-5,8-9,19H,2-3,6-7,10-18H2,1H3,(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assay				Bioorg Med Chem Lett 21: 5197-201 (2011) Article DOI: 10.1016/j.bmcl.2011.07.051 BindingDB Entry DOI: 10.7270/Q2PV6MNP
					More data for this Ligand-Target Pair
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Homo sapiens (Human))	BDBM50419068 (CHEMBL1823879) Show SMILES CCOc1ccccc1C(=O)NCC1(CCCCC1)N1CCN(CC1)C1CC1 Show InChI InChI=1S/C23H35N3O2/c1-2-28-21-9-5-4-8-20(21)22(27)24-18-23(12-6-3-7-13-23)26-16-14-25(15-17-26)19-10-11-19/h4-5,8-9,19H,2-3,6-7,10-18H2,1H3,(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50.1	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assay				Bioorg Med Chem Lett 21: 5197-201 (2011) Article DOI: 10.1016/j.bmcl.2011.07.051 BindingDB Entry DOI: 10.7270/Q2PV6MNP
					More data for this Ligand-Target Pair