BDBM50419075 CHEMBL1823888

SMILES: COc1ccccc1C(=O)NCC1(CCN(CC1)c1ccccc1)N1CCN(CC1)C(C)C

InChI Key: InChIKey=QQYVQGUQVYVEFA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50419075   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Homo sapiens (Human))	BDBM50419075 (CHEMBL1823888) Show SMILES COc1ccccc1C(=O)NCC1(CCN(CC1)c1ccccc1)N1CCN(CC1)C(C)C Show InChI InChI=1S/C27H38N4O2/c1-22(2)29-17-19-31(20-18-29)27(13-15-30(16-14-27)23-9-5-4-6-10-23)21-28-26(32)24-11-7-8-12-25(24)33-3/h4-12,22H,13-21H2,1-3H3,(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assay				Bioorg Med Chem Lett 21: 5197-201 (2011) Article DOI: 10.1016/j.bmcl.2011.07.051 BindingDB Entry DOI: 10.7270/Q2PV6MNP
					More data for this Ligand-Target Pair
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Homo sapiens (Human))	BDBM50419075 (CHEMBL1823888) Show SMILES COc1ccccc1C(=O)NCC1(CCN(CC1)c1ccccc1)N1CCN(CC1)C(C)C Show InChI InChI=1S/C27H38N4O2/c1-22(2)29-17-19-31(20-18-29)27(13-15-30(16-14-27)23-9-5-4-6-10-23)21-28-26(32)24-11-7-8-12-25(24)33-3/h4-12,22H,13-21H2,1-3H3,(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assay				Bioorg Med Chem Lett 21: 5197-201 (2011) Article DOI: 10.1016/j.bmcl.2011.07.051 BindingDB Entry DOI: 10.7270/Q2PV6MNP
					More data for this Ligand-Target Pair