BDBM50419081 CHEMBL1823679

SMILES: CN1CCN(CC1)C1(CNC(=O)c2ccccc2Cl)CCCCC1

InChI Key: InChIKey=KZCCUVIXZDJUHW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50419081   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Homo sapiens (Human))	BDBM50419081 (CHEMBL1823679) Show SMILES CN1CCN(CC1)C1(CNC(=O)c2ccccc2Cl)CCCCC1 Show InChI InChI=1S/C19H28ClN3O/c1-22-11-13-23(14-12-22)19(9-5-2-6-10-19)15-21-18(24)16-7-3-4-8-17(16)20/h3-4,7-8H,2,5-6,9-15H2,1H3,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human HCN1 heterologously expressed in HEK-293 cells after 30 mins by VIPR assay				Bioorg Med Chem Lett 21: 5197-201 (2011) Article DOI: 10.1016/j.bmcl.2011.07.051 BindingDB Entry DOI: 10.7270/Q2PV6MNP
					More data for this Ligand-Target Pair
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Homo sapiens (Human))	BDBM50419081 (CHEMBL1823679) Show SMILES CN1CCN(CC1)C1(CNC(=O)c2ccccc2Cl)CCCCC1 Show InChI InChI=1S/C19H28ClN3O/c1-22-11-13-23(14-12-22)19(9-5-2-6-10-19)15-21-18(24)16-7-3-4-8-17(16)20/h3-4,7-8H,2,5-6,9-15H2,1H3,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human HCN4 heterologously expressed in HEK-293 cells after 30 mins by VIPR assay				Bioorg Med Chem Lett 21: 5197-201 (2011) Article DOI: 10.1016/j.bmcl.2011.07.051 BindingDB Entry DOI: 10.7270/Q2PV6MNP
					More data for this Ligand-Target Pair