BDBM50419358 CHEMBL1916084

SMILES: Cc1ccc(cc1)S(=O)(=O)Nc1c(cnn1-c1ccccc1)C(=O)NC1CCCCC1

InChI Key: InChIKey=PYOYGEPMAQZLDH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50419358   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50419358 (CHEMBL1916084) Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1c(cnn1-c1ccccc1)C(=O)NC1CCCCC1 Show InChI InChI=1S/C23H26N4O3S/c1-17-12-14-20(15-13-17)31(29,30)26-22-21(23(28)25-18-8-4-2-5-9-18)16-24-27(22)19-10-6-3-7-11-19/h3,6-7,10-16,18,26H,2,4-5,8-9H2,1H3,(H,25,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at human FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 21: 6456-60 (2011) Article DOI: 10.1016/j.bmcl.2011.08.085 BindingDB Entry DOI: 10.7270/Q2WD41VZ
					More data for this Ligand-Target Pair