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SMILES: CCC(CC)NC(=O)c1nnn(c1NS(=O)(=O)c1ccc(C)cc1)-c1ccccc1

InChI Key: InChIKey=ZAEOSRJQGLBEGF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50419365   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
fMet-Leu-Phe receptor


(Homo sapiens (Human))		BDBM50419365
PNG
(CHEMBL1916261)
Show SMILES CCC(CC)NC(=O)c1nnn(c1NS(=O)(=O)c1ccc(C)cc1)-c1ccccc1
Show InChI InChI=1S/C21H25N5O3S/c1-4-16(5-2)22-21(27)19-20(26(25-23-19)17-9-7-6-8-10-17)24-30(28,29)18-13-11-15(3)12-14-18/h6-14,16,24H,4-5H2,1-3H3,(H,22,27)
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Article
PubMed
n/an/a 3.98E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Antagonist activity at human FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation by FLIPR assay

Bioorg Med Chem Lett 21: 6456-60 (2011)


Article DOI: 10.1016/j.bmcl.2011.08.085
BindingDB Entry DOI: 10.7270/Q2WD41VZ
More data for this
Ligand-Target Pair