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SMILES: CCC(CC)NC(=O)c1cnn(Cc2ccccc2)c1NS(=O)(=O)c1ccc(C)cc1

InChI Key: InChIKey=VAHWUGMTTGPDQF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50419370   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
fMet-Leu-Phe receptor


(Homo sapiens (Human))		BDBM50419370
PNG
(CHEMBL1916267)
Show SMILES CCC(CC)NC(=O)c1cnn(Cc2ccccc2)c1NS(=O)(=O)c1ccc(C)cc1
Show InChI InChI=1S/C23H28N4O3S/c1-4-19(5-2)25-23(28)21-15-24-27(16-18-9-7-6-8-10-18)22(21)26-31(29,30)20-13-11-17(3)12-14-20/h6-15,19,26H,4-5,16H2,1-3H3,(H,25,28)
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Article
PubMed
n/an/a 5.01E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Antagonist activity at human FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation by FLIPR assay

Bioorg Med Chem Lett 21: 6456-60 (2011)


Article DOI: 10.1016/j.bmcl.2011.08.085
BindingDB Entry DOI: 10.7270/Q2WD41VZ
More data for this
Ligand-Target Pair