BDBM50419375 CHEMBL1916276

SMILES: CC1CCCCC1NC(=O)c1cnn(c1NS(=O)(=O)c1ccc(C)cc1)-c1ccccc1

InChI Key: InChIKey=AYPVPRGQTUGNOF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50419375   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50419375 (CHEMBL1916276) Show SMILES CC1CCCCC1NC(=O)c1cnn(c1NS(=O)(=O)c1ccc(C)cc1)-c1ccccc1 Show InChI InChI=1S/C24H28N4O3S/c1-17-12-14-20(15-13-17)32(30,31)27-23-21(16-25-28(23)19-9-4-3-5-10-19)24(29)26-22-11-7-6-8-18(22)2/h3-5,9-10,12-16,18,22,27H,6-8,11H2,1-2H3,(H,26,29)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at human FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 21: 6456-60 (2011) Article DOI: 10.1016/j.bmcl.2011.08.085 BindingDB Entry DOI: 10.7270/Q2WD41VZ
					More data for this Ligand-Target Pair