BDBM50419377 CHEMBL1916278
SMILES: Cc1nn(c(NS(=O)(=O)c2ccc(C)cc2)c1C(=O)NC1CCOCC1)-c1ccccc1
InChI Key: InChIKey=QYEMDTRCNOFDPK-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fMet-Leu-Phe receptor (Homo sapiens (Human)) | BDBM50419377 (CHEMBL1916278) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Antagonist activity at human FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 21: 6456-60 (2011) Article DOI: 10.1016/j.bmcl.2011.08.085 BindingDB Entry DOI: 10.7270/Q2WD41VZ | |||||||||||
More data for this Ligand-Target Pair |