BDBM50419383 CHEMBL1916287

SMILES: C[C@H](NC(=O)c1c(C)nn(c1NS(=O)(=O)c1cccnc1)-c1ccc(F)cc1)C(C)(C)C

InChI Key: InChIKey=WJHDCBQZDWBYKV-HNNXBMFYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50419383   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50419383 (CHEMBL1916287) Show SMILES C[C@H](NC(=O)c1c(C)nn(c1NS(=O)(=O)c1cccnc1)-c1ccc(F)cc1)C(C)(C)C |r| Show InChI InChI=1S/C22H26FN5O3S/c1-14-19(21(29)25-15(2)22(3,4)5)20(27-32(30,31)18-7-6-12-24-13-18)28(26-14)17-10-8-16(23)9-11-17/h6-13,15,27H,1-5H3,(H,25,29)/t15-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at human FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation by FLIPR assay				Bioorg Med Chem Lett 21: 6456-60 (2011) Article DOI: 10.1016/j.bmcl.2011.08.085 BindingDB Entry DOI: 10.7270/Q2WD41VZ
					More data for this Ligand-Target Pair