BDBM50419445 CHEMBL1923023

SMILES: C(CSC(NC1CCCC1)=NCc1ccccc1)Cc1cnc[nH]1

InChI Key: InChIKey=XOWPFAUTGJEGMK-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50419445   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50419445 (CHEMBL1923023) Show SMILES C(CSC(NC1CCCC1)=NCc1ccccc1)Cc1cnc[nH]1 |w:10.11| Show InChI InChI=1S/C19H26N4S/c1-2-7-16(8-3-1)13-21-19(23-17-9-4-5-10-17)24-12-6-11-18-14-20-15-22-18/h1-3,7-8,14-15,17H,4-6,9-13H2,(H,20,22)(H,21,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	42.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
VU University Amsterdam Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counting				J Med Chem 54: 8136-47 (2011) Article DOI: 10.1021/jm201042n BindingDB Entry DOI: 10.7270/Q2MW2JDX
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50419445 (CHEMBL1923023) Show SMILES C(CSC(NC1CCCC1)=NCc1ccccc1)Cc1cnc[nH]1 |w:10.11| Show InChI InChI=1S/C19H26N4S/c1-2-7-16(8-3-1)13-21-19(23-17-9-4-5-10-17)24-12-6-11-18-14-20-15-22-18/h1-3,7-8,14-15,17H,4-6,9-13H2,(H,20,22)(H,21,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	42.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
VU University Amsterdam Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counting				J Med Chem 54: 8136-47 (2011) Article DOI: 10.1021/jm201042n BindingDB Entry DOI: 10.7270/Q2MW2JDX
					More data for this Ligand-Target Pair