BDBM50419448 CHEMBL1923026

SMILES: Clc1ccc(CNC(SCCCc2cnc[nH]2)=NC2CCCCC2)cc1Cl

InChI Key: InChIKey=SIDMDBDAIBEQFI-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50419448   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50419448 (CHEMBL1923026) Show SMILES Clc1ccc(CNC(SCCCc2cnc[nH]2)=NC2CCCCC2)cc1Cl |w:17.18| Show InChI InChI=1S/C20H26Cl2N4S/c21-18-9-8-15(11-19(18)22)12-24-20(26-16-5-2-1-3-6-16)27-10-4-7-17-13-23-14-25-17/h8-9,11,13-14,16H,1-7,10,12H2,(H,23,25)(H,24,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.02	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
VU University Amsterdam Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human H3 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counting				J Med Chem 54: 8136-47 (2011) Article DOI: 10.1021/jm201042n BindingDB Entry DOI: 10.7270/Q2MW2JDX
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50419448 (CHEMBL1923026) Show SMILES Clc1ccc(CNC(SCCCc2cnc[nH]2)=NC2CCCCC2)cc1Cl |w:17.18| Show InChI InChI=1S/C20H26Cl2N4S/c21-18-9-8-15(11-19(18)22)12-24-20(26-16-5-2-1-3-6-16)27-10-4-7-17-13-23-14-25-17/h8-9,11,13-14,16H,1-7,10,12H2,(H,23,25)(H,24,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	148	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
VU University Amsterdam Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counting				J Med Chem 54: 8136-47 (2011) Article DOI: 10.1021/jm201042n BindingDB Entry DOI: 10.7270/Q2MW2JDX
					More data for this Ligand-Target Pair