BDBM50419572 CHEMBL1934269

SMILES: C[C@H](NC(=O)c1c(C)nn(CC(F)(F)F)c1NS(=O)(=O)c1ccc(C)cc1)C(C)(C)C

InChI Key: InChIKey=QSWGEOMEAZNPPB-AWEZNQCLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50419572   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
fMet-Leu-Phe receptor (Homo sapiens (Human))	BDBM50419572 (CHEMBL1934269) Show SMILES C[C@H](NC(=O)c1c(C)nn(CC(F)(F)F)c1NS(=O)(=O)c1ccc(C)cc1)C(C)(C)C |r| Show InChI InChI=1S/C20H27F3N4O3S/c1-12-7-9-15(10-8-12)31(29,30)26-17-16(18(28)24-14(3)19(4,5)6)13(2)25-27(17)11-20(21,22)23/h7-10,14,26H,11H2,1-6H3,(H,24,28)/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at human recombinant FPR1 in expressed in HEK293 cells assessed as inhibition of FMLP-stimulated intracellular calcium mobilisati...				Bioorg Med Chem Lett 22: 532-6 (2011) Article DOI: 10.1016/j.bmcl.2011.10.090 BindingDB Entry DOI: 10.7270/Q27P90NM
					More data for this Ligand-Target Pair