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SMILES: C(OCc1ccccc1-c1ccccc1)C1CCCNC1

InChI Key: InChIKey=WIVOVQLTGHISNR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50419796   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Homo sapiens (Human))		BDBM50419796
PNG
(CHEMBL1950614)
Show SMILES C(OCc1ccccc1-c1ccccc1)C1CCCNC1
Show InChI InChI=1S/C19H23NO/c1-2-8-17(9-3-1)19-11-5-4-10-18(19)15-21-14-16-7-6-12-20-13-16/h1-5,8-11,16,20H,6-7,12-15H2
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Article
PubMed
n/an/a 4.17E+3n/an/an/an/an/an/a



The Ohio State University

Curated by ChEMBL


Assay Description
Antagonist activity at human nAChR alpha4/beta2 receptor expressed in HEK ts201 cells assessed as calcium accumulation by fluorescence analysis

Bioorg Med Chem Lett 22: 1797-813 (2012)


Article DOI: 10.1016/j.bmcl.2011.11.051
BindingDB Entry DOI: 10.7270/Q22Z16S2
More data for this
Ligand-Target Pair