BDBM50420045 CHEMBL2046662

SMILES: Fc1ccc(cc1F)C(=O)Nc1ccc(nc1)C(F)(F)F

InChI Key: InChIKey=HVSVOOJNAOXHRN-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50420045   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM50420045 (CHEMBL2046662) Show SMILES Fc1ccc(cc1F)C(=O)Nc1ccc(nc1)C(F)(F)F Show InChI InChI=1S/C13H7F5N2O/c14-9-3-1-7(5-10(9)15)12(21)20-8-2-4-11(19-6-8)13(16,17)18/h1-6H,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at KCNQ2/KCNQ3 expressed in CHO cells assessed as increase in KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induction ...				ACS Med Chem Lett 2: 481-484 (2011) Article DOI: 10.1021/ml200053x BindingDB Entry DOI: 10.7270/Q2R49RVJ
					More data for this Ligand-Target Pair