BDBM50420058 CHEMBL2046675

SMILES: Clc1ccc(NC(=O)c2ccc(cc2)-c2ccccc2)cn1

InChI Key: InChIKey=YOHQCNOYSLYXEJ-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50420058   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily E/KQT member 1 (Homo sapiens (Human))	BDBM50420058 (CHEMBL2046675) Show SMILES Clc1ccc(NC(=O)c2ccc(cc2)-c2ccccc2)cn1 Show InChI InChI=1S/C18H13ClN2O/c19-17-11-10-16(12-20-17)21-18(22)15-8-6-14(7-9-15)13-4-2-1-3-5-13/h1-12H,(H,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at KCNQ1/MINK expressed in CHO cells assessed as inhibition of KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induct...				ACS Med Chem Lett 2: 481-484 (2011) Article DOI: 10.1021/ml200053x BindingDB Entry DOI: 10.7270/Q2R49RVJ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM50420058 (CHEMBL2046675) Show SMILES Clc1ccc(NC(=O)c2ccc(cc2)-c2ccccc2)cn1 Show InChI InChI=1S/C18H13ClN2O/c19-17-11-10-16(12-20-17)21-18(22)15-8-6-14(7-9-15)13-4-2-1-3-5-13/h1-12H,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	260	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at KCNQ2/KCNQ3 expressed in CHO cells assessed as increase in KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induction ...				ACS Med Chem Lett 2: 481-484 (2011) Article DOI: 10.1021/ml200053x BindingDB Entry DOI: 10.7270/Q2R49RVJ
					More data for this Ligand-Target Pair