BDBM50420062 CHEMBL2046679

SMILES: Clc1cccc(c1)C(=O)Nc1ccc(Cl)nc1

InChI Key: InChIKey=RBVJTGOILWNECX-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50420062   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel beta subunit Mink/subunit Kv7.1 (Homo sapiens (Human))	BDBM50420062 (CHEMBL2046679) Show SMILES Clc1cccc(c1)C(=O)Nc1ccc(Cl)nc1 Show InChI InChI=1S/C12H8Cl2N2O/c13-9-3-1-2-8(6-9)12(17)16-10-4-5-11(14)15-7-10/h1-7H,(H,16,17)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at KCNQ1/MINK expressed in CHO cells assessed as inhibition of KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induct...				ACS Med Chem Lett 2: 481-484 (2011) Article DOI: 10.1021/ml200053x BindingDB Entry DOI: 10.7270/Q2R49RVJ
					More data for this Ligand-Target Pair
Voltage-gated potassium channel subunit Kv7.2/Kv7.3 (Homo sapiens (Human))	BDBM50420062 (CHEMBL2046679) Show SMILES Clc1cccc(c1)C(=O)Nc1ccc(Cl)nc1 Show InChI InChI=1S/C12H8Cl2N2O/c13-9-3-1-2-8(6-9)12(17)16-10-4-5-11(14)15-7-10/h1-7H,(H,16,17)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	270	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at KCNQ2/KCNQ3 expressed in CHO cells assessed as increase in KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induction ...				ACS Med Chem Lett 2: 481-484 (2011) Article DOI: 10.1021/ml200053x BindingDB Entry DOI: 10.7270/Q2R49RVJ
					More data for this Ligand-Target Pair