new BindingDB logo
myBDB logout

BDBM50420066 CHEMBL2046683

SMILES: Fc1cc(ccc1C(F)(F)F)C(=O)Nc1ccc(Cl)nc1

InChI Key: InChIKey=XXQQNUNEGMOWCU-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50420066   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated potassium channel beta subunit Mink/subunit Kv7.1


(Homo sapiens)
BDBM50420066
PNG
(CHEMBL2046683)
Show SMILES Fc1cc(ccc1C(F)(F)F)C(=O)Nc1ccc(Cl)nc1
Show InChI InChI=1S/C13H7ClF4N2O/c14-11-4-2-8(6-19-11)20-12(21)7-1-3-9(10(15)5-7)13(16,17)18/h1-6H,(H,20,21)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 3.40E+3n/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at KCNQ1/MINK expressed in CHO cells assessed as inhibition of KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induct...


Citation and Details
More data for this
Ligand-Target Pair
Voltage-gated potassium channel subunit Kv7.2/Kv7.3


(Homo sapiens)
BDBM50420066
PNG
(CHEMBL2046683)
Show SMILES Fc1cc(ccc1C(F)(F)F)C(=O)Nc1ccc(Cl)nc1
Show InChI InChI=1S/C13H7ClF4N2O/c14-11-4-2-8(6-19-11)20-12(21)7-1-3-9(10(15)5-7)13(16,17)18/h1-6H,(H,20,21)
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/an/an/a 370n/an/an/an/a


TBA

Assay Description
Agonist activity at KCNQ2/KCNQ3 expressed in CHO cells assessed as increase in KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induction ...


Citation and Details
More data for this
Ligand-Target Pair