BDBM50420069 CHEMBL2047507

SMILES: Fc1cc(ccc1C#N)C(=O)Nc1ccc(Cl)nc1

InChI Key: InChIKey=LPHSVGPLIZRCPP-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50420069   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily KQT member 2/3 (Homo sapiens (Human))	BDBM50420069 (CHEMBL2047507) Show SMILES Fc1cc(ccc1C#N)C(=O)Nc1ccc(Cl)nc1 Show InChI InChI=1S/C13H7ClFN3O/c14-12-4-3-10(7-17-12)18-13(19)8-1-2-9(6-16)11(15)5-8/h1-5,7H,(H,18,19)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at KCNQ2/KCNQ3 expressed in CHO cells assessed as increase in KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induction ...				ACS Med Chem Lett 2: 481-484 (2011) Article DOI: 10.1021/ml200053x BindingDB Entry DOI: 10.7270/Q2R49RVJ
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily E/KQT member 1 (Homo sapiens (Human))	BDBM50420069 (CHEMBL2047507) Show SMILES Fc1cc(ccc1C#N)C(=O)Nc1ccc(Cl)nc1 Show InChI InChI=1S/C13H7ClFN3O/c14-12-4-3-10(7-17-12)18-13(19)8-1-2-9(6-16)11(15)5-8/h1-5,7H,(H,18,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at KCNQ1/MINK expressed in CHO cells assessed as inhibition of KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induct...				ACS Med Chem Lett 2: 481-484 (2011) Article DOI: 10.1021/ml200053x BindingDB Entry DOI: 10.7270/Q2R49RVJ
					More data for this Ligand-Target Pair