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BDBM50420071 CHEMBL2046685

SMILES: Cc1ccc(cc1F)C(=O)Nc1ccc(Cl)nc1

InChI Key: InChIKey=BNMZYBREPGXDSW-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50420071   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated potassium channel beta subunit Mink/subunit Kv7.1


(Homo sapiens)
BDBM50420071
PNG
(CHEMBL2046685)
Show SMILES Cc1ccc(cc1F)C(=O)Nc1ccc(Cl)nc1
Show InChI InChI=1S/C13H10ClFN2O/c1-8-2-3-9(6-11(8)15)13(18)17-10-4-5-12(14)16-7-10/h2-7H,1H3,(H,17,18)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 3.30E+4n/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at KCNQ1/MINK expressed in CHO cells assessed as inhibition of KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induct...


Citation and Details
More data for this
Ligand-Target Pair
Voltage-gated potassium channel subunit Kv7.2/Kv7.3


(Homo sapiens)
BDBM50420071
PNG
(CHEMBL2046685)
Show SMILES Cc1ccc(cc1F)C(=O)Nc1ccc(Cl)nc1
Show InChI InChI=1S/C13H10ClFN2O/c1-8-2-3-9(6-11(8)15)13(18)17-10-4-5-12(14)16-7-10/h2-7H,1H3,(H,17,18)
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/an/an/a 280n/an/an/an/a


TBA

Assay Description
Agonist activity at KCNQ2/KCNQ3 expressed in CHO cells assessed as increase in KCl-induced 86Rb+ efflux incubated for 10 mins prior to KCl-induction ...


Citation and Details
More data for this
Ligand-Target Pair