BDBM50420362 CHEMBL2089182

SMILES: Fc1cc(cc(c1)C#Cc1cccc(n1)C#N)C#N

InChI Key: InChIKey=DUKGFMFYZDDUHV-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50420362   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50420362 (CHEMBL2089182) Show SMILES Fc1cc(cc(c1)C#Cc1cccc(n1)C#N)C#N Show InChI InChI=1S/C15H6FN3/c16-13-7-11(6-12(8-13)9-17)4-5-14-2-1-3-15(10-18)19-14/h1-3,6-8H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from mGluR5 in Sprague-Dawley rat brain membrane after 60 mins by liquid scintillation counting				ACS Med Chem Lett 3: 544-549 (2012) Article DOI: 10.1021/ml3000726 BindingDB Entry DOI: 10.7270/Q21C1Z4G
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50420362 (CHEMBL2089182) Show SMILES Fc1cc(cc(c1)C#Cc1cccc(n1)C#N)C#N Show InChI InChI=1S/C15H6FN3/c16-13-7-11(6-12(8-13)9-17)4-5-14-2-1-3-15(10-18)19-14/h1-3,6-8H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inverse agonist activity at rat mGluR5 expressed in HEK293A cells coexpressing Gqalpha assessed as inhibition of quisqualic-induced D-myo-inositol 1 ...				ACS Med Chem Lett 3: 544-549 (2012) Article DOI: 10.1021/ml3000726 BindingDB Entry DOI: 10.7270/Q21C1Z4G
					More data for this Ligand-Target Pair