Found 4 hits for monomerid = 50420507 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Protein-glutamine gamma-glutamyltransferase 2 (TG2)
(Homo sapiens (Human)) | BDBM50420507
(CHEMBL2086511)Show SMILES C=CC(=O)Nc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)OCc1ccccc1Oc1ccccc1 Show InChI InChI=1S/C27H27N3O6S/c1-2-26(31)28-22-12-14-24(15-13-22)37(33,34)30-18-16-29(17-19-30)27(32)35-20-21-8-6-7-11-25(21)36-23-9-4-3-5-10-23/h2-15H,1,16-20H2,(H,28,31) | PDB MMDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Evotec (UK) Ltd.
Curated by ChEMBL
| Assay Description Inhibition of human recombinant TG2 by fluorescent transamidation assay |
J Med Chem 55: 1021-46 (2012)
Article DOI: 10.1021/jm201310y BindingDB Entry DOI: 10.7270/Q2CN7560 |
More data for this Ligand-Target Pair | |
Coagulation factor XIII
(Homo sapiens (Human)) | BDBM50420507
(CHEMBL2086511)Show SMILES C=CC(=O)Nc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)OCc1ccccc1Oc1ccccc1 Show InChI InChI=1S/C27H27N3O6S/c1-2-26(31)28-22-12-14-24(15-13-22)37(33,34)30-18-16-29(17-19-30)27(32)35-20-21-8-6-7-11-25(21)36-23-9-4-3-5-10-23/h2-15H,1,16-20H2,(H,28,31) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a | n/a |
Evotec (UK) Ltd.
Curated by ChEMBL
| Assay Description Inhibition of thrombin activated human F13a by fluorescent transamidation assay |
J Med Chem 55: 1021-46 (2012)
Article DOI: 10.1021/jm201310y BindingDB Entry DOI: 10.7270/Q2CN7560 |
More data for this Ligand-Target Pair | |
Transglutaminase-3 (TG3)
(Homo sapiens (Human)) | BDBM50420507
(CHEMBL2086511)Show SMILES C=CC(=O)Nc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)OCc1ccccc1Oc1ccccc1 Show InChI InChI=1S/C27H27N3O6S/c1-2-26(31)28-22-12-14-24(15-13-22)37(33,34)30-18-16-29(17-19-30)27(32)35-20-21-8-6-7-11-25(21)36-23-9-4-3-5-10-23/h2-15H,1,16-20H2,(H,28,31) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Evotec (UK) Ltd.
Curated by ChEMBL
| Assay Description Inhibition of thrombin activated human TG3 by fluorescent transamidation assay |
J Med Chem 55: 1021-46 (2012)
Article DOI: 10.1021/jm201310y BindingDB Entry DOI: 10.7270/Q2CN7560 |
More data for this Ligand-Target Pair | |
Transglutaminase-1 (TG1)
(Homo sapiens (Human)) | BDBM50420507
(CHEMBL2086511)Show SMILES C=CC(=O)Nc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)OCc1ccccc1Oc1ccccc1 Show InChI InChI=1S/C27H27N3O6S/c1-2-26(31)28-22-12-14-24(15-13-22)37(33,34)30-18-16-29(17-19-30)27(32)35-20-21-8-6-7-11-25(21)36-23-9-4-3-5-10-23/h2-15H,1,16-20H2,(H,28,31) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Evotec (UK) Ltd.
Curated by ChEMBL
| Assay Description Inhibition of human recombinant TG1 by fluorescent transamidation assay |
J Med Chem 55: 1021-46 (2012)
Article DOI: 10.1021/jm201310y BindingDB Entry DOI: 10.7270/Q2CN7560 |
More data for this Ligand-Target Pair | |