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SMILES: COc1ccccc1CC(CN1CCC2(CC1)OCCc1ccsc21)C(=O)N(C)C

InChI Key: InChIKey=TXGNMJQHEWURGN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50420822   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nociceptin receptor


(Homo sapiens (Human))		BDBM50420822
PNG
(CHEMBL2088046)
Show SMILES COc1ccccc1CC(CN1CCC2(CC1)OCCc1ccsc21)C(=O)N(C)C
Show InChI InChI=1S/C24H32N2O3S/c1-25(2)23(27)20(16-19-6-4-5-7-21(19)28-3)17-26-12-10-24(11-13-26)22-18(8-14-29-24)9-15-30-22/h4-7,9,15,20H,8,10-14,16-17H2,1-3H3
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Article
PubMed
>10n/an/an/an/an/an/an/an/a



Centro de Investigaci�n Lilly

Curated by ChEMBL


Assay Description
Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay

J Med Chem 55: 4955-67 (2012)


Article DOI: 10.1021/jm201629q
BindingDB Entry DOI: 10.7270/Q2TQ62SQ
More data for this
Ligand-Target Pair