null

SMILES: CC(C)c1cc(Nc2nc(NCc3cccnc3)ncc2Br)[nH]n1

InChI Key: InChIKey=JNSMYVIVQDWCFM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50420967   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50420967 (CHEMBL2088256) Show SMILES CC(C)c1cc(Nc2nc(NCc3cccnc3)ncc2Br)[nH]n1 Show InChI InChI=1S/C16H18BrN7/c1-10(2)13-6-14(24-23-13)21-15-12(17)9-20-16(22-15)19-8-11-4-3-5-18-7-11/h3-7,9-10H,8H2,1-2H3,(H3,19,20,21,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant N terminal GST-tagged human KDR (805 to 1356) expressed in baculovirus infected Sf9 cells after 90 mins by caliper mobility...				J Med Chem 55: 5003-12 (2012) Article DOI: 10.1021/jm3004043 BindingDB Entry DOI: 10.7270/Q25X2B62
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50420967 (CHEMBL2088256) Show SMILES CC(C)c1cc(Nc2nc(NCc3cccnc3)ncc2Br)[nH]n1 Show InChI InChI=1S/C16H18BrN7/c1-10(2)13-6-14(24-23-13)21-15-12(17)9-20-16(22-15)19-8-11-4-3-5-18-7-11/h3-7,9-10H,8H2,1-2H3,(H3,19,20,21,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63.1	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant N terminal GST-tagged human FGFR1 (456 to 765) expressed in baculovirus infected Sf21 cells after 40 mins by caliper mobili...				J Med Chem 55: 5003-12 (2012) Article DOI: 10.1021/jm3004043 BindingDB Entry DOI: 10.7270/Q25X2B62
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50420967 (CHEMBL2088256) Show SMILES CC(C)c1cc(Nc2nc(NCc3cccnc3)ncc2Br)[nH]n1 Show InChI InChI=1S/C16H18BrN7/c1-10(2)13-6-14(24-23-13)21-15-12(17)9-20-16(22-15)19-8-11-4-3-5-18-7-11/h3-7,9-10H,8H2,1-2H3,(H3,19,20,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant N terminal His6-tagged human IGF1R (959 to end) expressed in baculovirus infected Sf21 cells after 80 mins by caliper mobil...				J Med Chem 55: 5003-12 (2012) Article DOI: 10.1021/jm3004043 BindingDB Entry DOI: 10.7270/Q25X2B62
					More data for this Ligand-Target Pair