BDBM50421092 CHEMBL2088337

SMILES: OP(O)(=O)C(Nc1cncc(Cc2ccccc2)c1)P(O)(O)=O

InChI Key: InChIKey=PWROIUWONVACKT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50421092   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Farnesyl diphosphate synthase (Homo sapiens (Human))	BDBM50421092 (CHEMBL2088337) Show SMILES OP(O)(=O)C(Nc1cncc(Cc2ccccc2)c1)P(O)(O)=O Show InChI InChI=1S/C13H16N2O6P2/c16-22(17,18)13(23(19,20)21)15-12-7-11(8-14-9-12)6-10-4-2-1-3-5-10/h1-5,7-9,13,15H,6H2,(H2,16,17,18)(H2,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Curated by ChEMBL					Assay Description Inhibition of human His6-tagged recombinant FPPS expressed in Escherichia coli BL21(DE3) using GPP and [3H]IPP as substrate incubated for 5 mins prio...				Bioorg Med Chem 20: 5583-91 (2012) Article DOI: 10.1016/j.bmc.2012.07.019 BindingDB Entry DOI: 10.7270/Q2J67J6M
					More data for this Ligand-Target Pair