BDBM50421268 CHEMBL2087886

SMILES: C(Nc1ncnc2nc(-c3ccccc3)n(-c3ccccc3)c12)[C@@H]1CCCO1

InChI Key: InChIKey=MUEGQYXBUWHEQT-SFHVURJKSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50421268   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine kinase non-receptor protein 2 (Homo sapiens (Human))	BDBM50421268 (CHEMBL2087886) Show SMILES C(Nc1ncnc2nc(-c3ccccc3)n(-c3ccccc3)c12)[C@@H]1CCCO1 |r| Show InChI InChI=1S/C22H21N5O/c1-3-8-16(9-4-1)22-26-21-19(27(22)17-10-5-2-6-11-17)20(24-15-25-21)23-14-18-12-7-13-28-18/h1-6,8-11,15,18H,7,12-14H2,(H,23,24,25)/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged ACK1 expressed in baculovirus infected Hi5 cells assessed as inhibition of autophosphorylation after 2 hrs by EL...				Bioorg Med Chem Lett 22: 6212-7 (2012) Article DOI: 10.1016/j.bmcl.2012.08.020 BindingDB Entry DOI: 10.7270/Q2VH5Q4X
					More data for this Ligand-Target Pair