BDBM50421359 CHEMBL145075
SMILES: CCCCN1CCC(COC(=O)c2c3OCCn3c3ccccc23)CC1
InChI Key: InChIKey=PDKWAHWPUBNFCD-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Serotonin 4 (5-HT4) receptor (Sus scrofa) | BDBM50421359 (CHEMBL145075) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.0794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Compound was evaluated for its ability to inhibit the binding of 5-HT4 receptor radioligand [125I]SB 207710 to piglet hippocampal membrane | Citation and Details Article DOI: 10.1016/S0960-894X(01)80176-1 BindingDB Entry DOI: 10.7270/Q25T3MSB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HTR4 (GUINEA PIG) | BDBM50421359 (CHEMBL145075) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Ability to block 5-HT4 receptor mediated effect of 5-HT was assessed in the guinea-pig distal colon longitudinal muscle myenteric plexus preparation ... | Citation and Details Article DOI: 10.1016/S0960-894X(01)80176-1 BindingDB Entry DOI: 10.7270/Q25T3MSB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HTR4 (GUINEA PIG) | BDBM50421359 (CHEMBL145075) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Ability to antagonize 5-HT-evoked contractions mediated through 5-hydroxytryptamine 4 receptor activation in the guinea pig distal colon LMMP | J Med Chem 38: 4760-3 (1996) BindingDB Entry DOI: 10.7270/Q2B56M1M | |||||||||||
More data for this Ligand-Target Pair |