BDBM50421360 CHEMBL358119::SB-207058

SMILES: CCCCN1CCC(COC(=O)c2c3OCCCn3c3ccccc23)CC1

InChI Key: InChIKey=HATXPTCDDBRERG-UHFFFAOYSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50421360   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin 4 (5-HT4) receptor (Sus scrofa)	BDBM50421360 (CHEMBL358119 | SB-207058) Show SMILES CCCCN1CCC(COC(=O)c2c3OCCCn3c3ccccc23)CC1 Show InChI InChI=1S/C22H30N2O3/c1-2-3-11-23-13-9-17(10-14-23)16-27-22(25)20-18-7-4-5-8-19(18)24-12-6-15-26-21(20)24/h4-5,7-8,17H,2-3,6,9-16H2,1H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.0631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound was evaluated for its ability to inhibit the binding of 5-HT4 receptor radioligand [125I]SB 207710 to piglet hippocampal membrane				Citation and Details Article DOI: 10.1016/S0960-894X(01)80176-1 BindingDB Entry DOI: 10.7270/Q25T3MSB
					More data for this Ligand-Target Pair
HTR4 (GUINEA PIG)	BDBM50421360 (CHEMBL358119 | SB-207058) Show SMILES CCCCN1CCC(COC(=O)c2c3OCCCn3c3ccccc23)CC1 Show InChI InChI=1S/C22H30N2O3/c1-2-3-11-23-13-9-17(10-14-23)16-27-22(25)20-18-7-4-5-8-19(18)24-12-6-15-26-21(20)24/h4-5,7-8,17H,2-3,6,9-16H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.0251	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Ability to block 5-HT4 receptor mediated effect of 5-HT was assessed in the guinea-pig distal colon longitudinal muscle myenteric plexus preparation ...				Citation and Details Article DOI: 10.1016/S0960-894X(01)80176-1 BindingDB Entry DOI: 10.7270/Q25T3MSB
					More data for this Ligand-Target Pair
HTR4 (GUINEA PIG)	BDBM50421360 (CHEMBL358119 | SB-207058) Show SMILES CCCCN1CCC(COC(=O)c2c3OCCCn3c3ccccc23)CC1 Show InChI InChI=1S/C22H30N2O3/c1-2-3-11-23-13-9-17(10-14-23)16-27-22(25)20-18-7-4-5-8-19(18)24-12-6-15-26-21(20)24/h4-5,7-8,17H,2-3,6,9-16H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Ability to antagonize 5-HT-evoked contractions mediated through 5-hydroxytryptamine 4 receptor activation in the guinea pig distal colon LMMP				J Med Chem 38: 4760-3 (1996) BindingDB Entry DOI: 10.7270/Q2B56M1M
					More data for this Ligand-Target Pair