BDBM50422268 GLUTATHIONE::GSH
SMILES: N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
InChI Key: InChIKey=RWSXRVCMGQZWBV-WDSKDSINSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Glyoxalase I (Homo sapiens (Human)) | BDBM50422268 (GLUTATHIONE | GSH) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | PubMed | 9.55E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uniroyal Chemical Co., Inc. Curated by ChEMBL | Assay Description Inhibition constant of compound against binding of Yeast Glyoxalase I | J Med Chem 31: 1396-406 (1988) BindingDB Entry DOI: 10.7270/Q2P55QQJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathione-binding protein (GbpAHp) (Haemophilus parasuis) | BDBM50422268 (GLUTATHIONE | GSH) | PDB GoogleScholar AffyNet | Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | 7.4 | 37 |
Ghent University | Assay Description Experiments were carried out using a VP-ITC MicroCalorimeter (MicroCal) at 37°C, and data were analyzed using the Origen ITC analysis software packag... | BMC Biochem 12: 59 (2011) Article DOI: 10.1186/1471-2091-12-59 BindingDB Entry DOI: 10.7270/Q2B27T57 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathione-binding protein (GbpAPm) (Pasteurella multocida) | BDBM50422268 (GLUTATHIONE | GSH) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 260 | n/a | n/a | n/a | 7.4 | 37 |
Ghent University | Assay Description Experiments were carried out using a VP-ITC MicroCalorimeter (MicroCal) at 37°C, and data were analyzed using the Origen ITC analysis software packag... | BMC Biochem 12: 59 (2011) Article DOI: 10.1186/1471-2091-12-59 BindingDB Entry DOI: 10.7270/Q2B27T57 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein G9a (G9a) (Homo sapiens (Human)) | BDBM50422268 (GLUTATHIONE | GSH) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Curated by ChEMBL | Assay Description Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 ... | Bioorg Med Chem Lett 28: 1234-1238 (2018) Article DOI: 10.1016/j.bmcl.2018.02.043 BindingDB Entry DOI: 10.7270/Q24Q7XKJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human)) | BDBM50422268 (GLUTATHIONE | GSH) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Radboud University Curated by ChEMBL | Assay Description Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 ... | Bioorg Med Chem Lett 28: 1234-1238 (2018) Article DOI: 10.1016/j.bmcl.2018.02.043 BindingDB Entry DOI: 10.7270/Q24Q7XKJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathione-binding protein (GbpAAp) (Actinobacillus pleuropneumoniae) | BDBM50422268 (GLUTATHIONE | GSH) | PDB GoogleScholar AffyNet | Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.58E+3 | n/a | n/a | n/a | 7.4 | 37 |
Ghent University | Assay Description Experiments were carried out using a VP-ITC MicroCalorimeter (MicroCal) at 37°C, and data were analyzed using the Origen ITC analysis software packag... | BMC Biochem 12: 59 (2011) Article DOI: 10.1186/1471-2091-12-59 BindingDB Entry DOI: 10.7270/Q2B27T57 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathione S-transferase kappa 1 (Homo sapiens (Human)) | BDBM50422268 (GLUTATHIONE | GSH) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | DrugBank Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Sidi Mohamed Ben Abdellah Curated by ChEMBL | Assay Description Affinity towards recombinant Glutathione S-transferase (GST) Enzyme. | J Med Chem 41: 2278-88 (1998) Article DOI: 10.1021/jm970518m BindingDB Entry DOI: 10.7270/Q2154G56 | |||||||||||
More data for this Ligand-Target Pair |