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BDBM50422348 CHEMBL2303985

SMILES: OC[C@@H]1O[C@@H](Oc2cc(O)cc(O)c2C(=O)CCc2ccc(O)c(NC(=O)CBr)c2)[C@@H](O)[C@@H](O)[C@@H]1O

InChI Key: InChIKey=CUFHFMHHSMPJBW-MPQLGERFSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50422348   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 1 (SGLT1)


(Homo sapiens (Human))		BDBM50422348
PNG
(CHEMBL2303985)
Show SMILES OC[C@@H]1O[C@@H](Oc2cc(O)cc(O)c2C(=O)CCc2ccc(O)c(NC(=O)CBr)c2)[C@@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C23H26BrNO11/c24-8-18(31)25-12-5-10(1-3-13(12)28)2-4-14(29)19-15(30)6-11(27)7-16(19)35-23-22(34)21(33)20(32)17(9-26)36-23/h1,3,5-7,17,20-23,26-28,30,32-34H,2,4,8-9H2,(H,25,31)/t17-,20+,21-,22-,23+/m0/s1
PDB

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PC cid
PC sid
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Similars
PubMed
 7.70E+3n/an/an/an/an/an/an/an/a



Max-Planck-Institut f£r molekulare Physiologie

Curated by ChEMBL


Assay Description
Binding affinity against Sodium/glucose co-transporter of isolated renal brush border membranes.

J Med Chem 43: 1692-8 (2000)


BindingDB Entry DOI: 10.7270/Q261112H
More data for this
Ligand-Target Pair