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SMILES: CCC(CC)n1cc2CCN(c3ccc(OC(F)(F)F)cc3C)c3nc(C)cc1c23

InChI Key: InChIKey=FSRSPCLMXBHMAB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50423378   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50423378
PNG
(CHEMBL250603)
Show SMILES CCC(CC)n1cc2CCN(c3ccc(OC(F)(F)F)cc3C)c3nc(C)cc1c23
Show InChI InChI=1S/C23H26F3N3O/c1-5-17(6-2)29-13-16-9-10-28(22-21(16)20(29)12-15(4)27-22)19-8-7-18(11-14(19)3)30-23(24,25)26/h7-8,11-13,17H,5-6,9-10H2,1-4H3
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n/an/a 79n/an/an/an/an/an/a



GlaxoSmithkline

Curated by ChEMBL


Assay Description
Displacement of [125I]CRF from human recombinant CRF1 receptor expressed in CHO cell membrane

Bioorg Med Chem Lett 17: 5218-21 (2007)


Article DOI: 10.1016/j.bmcl.2007.06.077
BindingDB Entry DOI: 10.7270/Q2P55PS1
More data for this
Ligand-Target Pair