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SMILES: CCC(CC)n1cc2CCN(c3ccc(OC)cc3C)c3nc(C)cc1c23

InChI Key: InChIKey=FLRXQZULCQIJEB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50423385   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50423385
PNG
(CHEMBL248962)
Show SMILES CCC(CC)n1cc2CCN(c3ccc(OC)cc3C)c3nc(C)cc1c23
Show InChI InChI=1S/C23H29N3O/c1-6-18(7-2)26-14-17-10-11-25(20-9-8-19(27-5)12-15(20)3)23-22(17)21(26)13-16(4)24-23/h8-9,12-14,18H,6-7,10-11H2,1-5H3
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n/an/a 13n/an/an/an/an/an/a



GlaxoSmithkline

Curated by ChEMBL


Assay Description
Displacement of [125I]CRF from human recombinant CRF1 receptor expressed in CHO cell membrane

Bioorg Med Chem Lett 17: 5218-21 (2007)


Article DOI: 10.1016/j.bmcl.2007.06.077
BindingDB Entry DOI: 10.7270/Q2P55PS1
More data for this
Ligand-Target Pair