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SMILES: COc1ccccc1Oc1cccc(CN2CCC3(CC2)CCN(CC3)C(=O)c2ccc(Cl)cc2)c1

InChI Key: InChIKey=WUCNLBAXCJABQR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50423492   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 8


(Homo sapiens (Human))		BDBM50423492
PNG
(CHEMBL409648)
Show SMILES COc1ccccc1Oc1cccc(CN2CCC3(CC2)CCN(CC3)C(=O)c2ccc(Cl)cc2)c1
Show InChI InChI=1S/C30H33ClN2O3/c1-35-27-7-2-3-8-28(27)36-26-6-4-5-23(21-26)22-32-17-13-30(14-18-32)15-19-33(20-16-30)29(34)24-9-11-25(31)12-10-24/h2-12,21H,13-20,22H2,1H3
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Article
PubMed
n/an/a 12n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Antagonist activity at CCR8 receptor

J Med Chem 51: 1162-78 (2008)


Article DOI: 10.1021/jm070543k
BindingDB Entry DOI: 10.7270/Q2C24XMG
More data for this
Ligand-Target Pair