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BDBM50423930 CHEMBL2313033

SMILES: Clc1cc(C2=NN(C(C2)c2ccc(Cl)cc2)c2nc(cs2)-c2ccc(Cl)cc2)c(Cl)s1

InChI Key: InChIKey=OIHZDLSMYLNRJK-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50423930   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Xanthine dehydrogenase/oxidase


(Rattus norvegicus)		BDBM50423930
PNG
(CHEMBL2313033)
Show SMILES Clc1cc(C2=NN(C(C2)c2ccc(Cl)cc2)c2nc(cs2)-c2ccc(Cl)cc2)c(Cl)s1 |t:4|
Show InChI InChI=1S/C22H13Cl4N3S2/c23-14-5-1-12(2-6-14)18-11-30-22(27-18)29-19(13-3-7-15(24)8-4-13)10-17(28-29)16-9-20(25)31-21(16)26/h1-9,11,19H,10H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.60E+4n/an/an/an/an/an/a



Swami Ramanand Teerth Marathwada University

Curated by ChEMBL


Assay Description
Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...

Bioorg Med Chem 21: 365-72 (2012)


Article DOI: 10.1016/j.bmc.2012.09.060
BindingDB Entry DOI: 10.7270/Q2RV0Q0R
More data for this
Ligand-Target Pair